What is Eastern Equine Encephalitis (EEE)?

EEE is a viral disease transmitted to humans through the bite of infected mosquitoes, which can cause severe neurological conditions.

When was the last human death from EEE in South Carolina?

The last human death from EEE in South Carolina was reported in 2003.

Are there any vaccines or specific treatments for EEE?

No, there are currently no vaccines or specific treatments available for EEE in humans.

What preventive measures can be taken against EEE?

Preventive measures focus on avoiding mosquito bites, including wearing protective clothing and using EPA-registered mosquito repellents.

October 8, 2025

Beaufort County Reports First Human Death from EEE in Two Decades

Beaufort County, October 8, 2025

News Summary

The South Carolina Department of Public Health confirmed the first human death from Eastern Equine Encephalitis (EEE) virus since 2003 in Beaufort County. This fatal case raises concerns about the resurgence of the mosquito-borne disease, which poses severe health risks. With no vaccines or specific treatments available, health officials emphasize the importance of preventive measures against mosquito bites. Enhanced mosquito control efforts are underway, aiming to protect vulnerable populations, particularly those over 50 and children under 15.

Beaufort County, South Carolina Reports First Human Death from Eastern Equine Encephalitis in Over Two Decades

The South Carolina Department of Public Health (DPH) has confirmed the first human death from the eastern equine encephalitis (EEE) virus since 2003. The fatality, reported on September 19, involved a resident from Beaufort County. This incident signifies the first human case of EEE in South Carolina since 2020, raising alarm among health officials about the resurgence of this mosquito-borne illness.

EEE is primarily transmitted to humans through the bite of infected mosquitoes. It is important to note that the virus is not spread from person to person. Upon infection, individuals may experience either a febrile illness without neurological symptoms or severe neurological conditions, which can include inflammation of the brain (encephalitis) or spinal cord (meningitis). According to the CDC, approximately 30% of individuals who develop severe EEE die within 10 days, and many survivors face long-term neurological issues such as seizures, memory problems, and cognitive impairment.

Currently, there are no vaccines or specific treatments available for EEE in humans, emphasizing the importance of mosquito bite prevention. The American Mosquito Control Association recommends individuals wear long sleeves and long pants, opting for light-colored and loose-fitting clothing when outdoors. It is also advised to utilize EPA-registered mosquito repellents that contain DEET, picaridin, or oil of lemon eucalyptus. For enhanced protection, clothing treated with permethrin can be effective against mosquito bites.

In 2025, state and county officials identified ten horses infected with the EEE virus across multiple counties, including Aiken, Colleton, Horry, Jasper, Orangeburg, and Sumter. Following the confirmed human case, Beaufort County has intensified mosquito control efforts, incorporating truck-based spraying and planned helicopter applications to cover wider areas. Additionally, increased mosquito trapping and monitoring initiatives have been launched in the region.

Local health officials stress that community-level efforts in mosquito control are crucial. This includes managing yard maintenance and coordinated spraying activities. EEE is typically more prevalent in Atlantic and Gulf Coast states, as well as around the Great Lakes, particularly near freshwater hardwood swamps. Vulnerable populations include individuals over 50 years of age and children under 15, who are at higher risk for severe neurological complications stemming from EEE.

Symptoms of EEE generally develop four to ten days following a mosquito bite and may include fever, headache, vomiting, diarrhea, and notable behavioral changes. The DPH has urged residents to take practical steps to eliminate mosquito breeding sites by eliminating standing water and managing overgrown vegetation. Local health departments remain in close collaboration with Clemson University and the CDC for ongoing surveillance and response to both human and animal cases of mosquito-borne diseases.

Frequently Asked Questions

What is Eastern Equine Encephalitis (EEE)?

EEE is a viral disease transmitted to humans through the bite of infected mosquitoes, which can cause severe neurological conditions.
When was the last human death from EEE in South Carolina?

The last human death from EEE in South Carolina was reported in 2003.
What percentage of those with severe EEE die within 10 days?

Approximately 30% of individuals who develop severe EEE die within 10 days, according to the CDC.
Are there any vaccines or specific treatments for EEE?

No, there are currently no vaccines or specific treatments available for EEE in humans.
What preventive measures can be taken against EEE?

Preventive measures focus on avoiding mosquito bites, including wearing protective clothing and using EPA-registered mosquito repellents.

Key Features of EEE

Feature	Details
Transmission	Infected mosquitoes
Reported cases	First human case in South Carolina since 2020
Fatality rate	Approximately 30% for severe cases
Prevention	Avoiding mosquito bites, using repellents
Vulnerable populations	Individuals over 50 and children under 15
Symptoms	Fever, headache, vomiting, and behavioral changes

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Author: STAFF HERE BEAUFORT

The HERE Beaufort Staff Writers are a collaborative team of journalists, editors, and local contributors passionate about delivering accurate, timely information to the Beaufort community. As part of the HEREcity.com Network, which powers over 100 U.S. city sites including HEREcolumbia.com, our staff draws on collective experience in South Carolina journalism to cover everything from business sales and real estate developments to dining deals and community initiatives. Our Expertise and Background: Local Roots in Beaufort : Our team includes lifelong Beaufort residents and SC natives with deep knowledge of the area’s history, economy, and culture. We’ve covered key events like the recent sale of the historic Crofts Block Building, Beaufort’s equestrian heritage, and growth in local tech and education sectors (e.g., BeaufortTechnical College programs). Collective Experience: With over 50 combined years in journalism, our staff has backgrounds in print, digital media, and community reporting. We prioritize fact-based stories, drawing from sources like the Beaufort Chamber of Commerce, city government records, and on-the-ground interviews. Commitment to Quality: Every article is a group effort, involving research, editing, and verification to ensure reliability. We adhere to journalistic standards, citing credible sources and updating content as new details emerge.

STAFF HERE BEAUFORT

The HERE Beaufort Staff Writers are a collaborative team of journalists, editors, and local contributors passionate about delivering accurate, timely information to the Beaufort community. As part of the HEREcity.com Network, which powers over 100 U.S. city sites including HEREcolumbia.com, our staff draws on collective experience in South Carolina journalism to cover everything from business sales and real estate developments to dining deals and community initiatives. Our Expertise and Background: Local Roots in Beaufort : Our team includes lifelong Beaufort residents and SC natives with deep knowledge of the area’s history, economy, and culture. We’ve covered key events like the recent sale of the historic Crofts Block Building, Beaufort’s equestrian heritage, and growth in local tech and education sectors (e.g., BeaufortTechnical College programs). Collective Experience: With over 50 combined years in journalism, our staff has backgrounds in print, digital media, and community reporting. We prioritize fact-based stories, drawing from sources like the Beaufort Chamber of Commerce, city government records, and on-the-ground interviews. Commitment to Quality: Every article is a group effort, involving research, editing, and verification to ensure reliability. We adhere to journalistic standards, citing credible sources and updating content as new details emerge.

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