News Summary
Downtown Beaufort is set to welcome Sister Sister Deli & Market this fall, a neighborhood deli and gourmet market owned by sisters Sami and Dani Mussman. Located at 403 Carteret Street, the venue will offer Southern-inspired dishes, charcuterie options, and specialty meals like pickled shrimp and Old Bay shrimp melt. Emphasizing sustainability and local sourcing, the deli plans to open by October, inviting the community to engage through social media updates as renovations continue.
New Sister Sister Deli & Market Set to Open in Downtown Beaufort This Fall
Downtown Beaufort will soon welcome a new dining venue with the anticipated opening of Sister Sister Deli & Market this fall. Owned by sisters Sami and Dani Mussman, the deli is set to occupy the space at 403 Carteret Street, formerly home to the Italian eatery Griffin Market, which closed its doors in 2024.
Sister Sister Deli & Market is designed to serve as both a neighborhood deli and a gourmet market, offering a variety of culinary options. While the full menu is still being finalized, early indications suggest a focus on Southern-inspired dishes along with an array of charcuterie and deli offerings featuring only American-made ingredients and products. Guests can expect options such as cut-to-order cheese, made-to-order sandwiches, house-made deli meats, pickles, and condiments, as well as a selection of small-batch goods sourced from U.S. makers.
The planned lunch menu is particularly intriguing, featuring items such as pickled shrimp, confit chicken wings, and Old Bay shrimp melt. Additionally, visitors will be able to discover house specialties that the deli’s owners plan to highlight.
Renovation and Discovery
Renovations of the space, which began in June 2023, have already uncovered interesting historical elements from the building’s past. Among the discoveries was a planter box that has been creatively repurposed into a bench, along with hand-painted signs from its previous life as an auto shop. Workers noted that they found three distinct layers of flooring during the renovation process. The building is also scheduled for repainting, with work to begin in July.
Community Connection and Sustainability
Sister Sister Deli & Market emphasizes sustainability, adhering to principles that support local and regional producers. This commitment promises to appeal to customers who are increasingly concerned with where their food comes from and its environmental impact.
Opening Timeline and Future Updates
While an exact opening date has not yet been announced, the deli is aiming for a launch by October. Once operational, Sister Sister Deli & Market plans to serve as a popular spot for lunch breaks, snacks, and supplying dinner party charcuterie board crafting needs. As preparations continue, the owners encourage the community to follow their progress through updates and sneak peeks available on their Facebook and Instagram pages.
As Downtown Beaufort evolves, Sister Sister Deli & Market is poised to become a noticeable addition to the local food scene, with a fresh perspective on deli dining and market offerings slated to open within months.
Deeper Dive: News & Info About This Topic
HERE Resources
Sister Sister Deli and Market Set to Open in Beaufort
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Additional Resources
- What Now: Sister Sister Deli & Market in Beaufort
- Wikipedia: Southern Cuisine
- Your Island News: New Southern Restaurant
- Google Search: Sister Sister Deli Beaufort
- Perth is OK: New Bars and Restaurants
- Encyclopedia Britannica: Charcuterie
- Perth is OK: Best Pizza in Perth
- Google News: Restaurant Openings Beaufort

Author: STAFF HERE BEAUFORT
The HERE Beaufort Staff Writers are a collaborative team of journalists, editors, and local contributors passionate about delivering accurate, timely information to the Beaufort community. As part of the HEREcity.com Network, which powers over 100 U.S. city sites including HEREcolumbia.com, our staff draws on collective experience in South Carolina journalism to cover everything from business sales and real estate developments to dining deals and community initiatives. Our Expertise and Background: Local Roots in Beaufort : Our team includes lifelong Beaufort residents and SC natives with deep knowledge of the area’s history, economy, and culture. We’ve covered key events like the recent sale of the historic Crofts Block Building, Beaufort’s equestrian heritage, and growth in local tech and education sectors (e.g., BeaufortTechnical College programs). Collective Experience: With over 50 combined years in journalism, our staff has backgrounds in print, digital media, and community reporting. We prioritize fact-based stories, drawing from sources like the Beaufort Chamber of Commerce, city government records, and on-the-ground interviews. Commitment to Quality: Every article is a group effort, involving research, editing, and verification to ensure reliability. We adhere to journalistic standards, citing credible sources and updating content as new details emerge.

